Bone tissue response following local drug delivery of bisphosphonate through titanium oxide nanotube implants in a rabbit model.

David H KwonSang J LeeUlf M E WikesjöPetra H JohanssonCarina B JohanssonYoung-Taeg Sul

Published in: Journal of clinical periodontology (2017)

TiO2 nanotube implants may prove to be a significant delivery system for drugs or biologic agents aimed at supporting local bone formation. Additional study of candidate drugs/agents, optimized dosage and release kinetics is needed prior to evaluation in clinical settings.

Keyphrases

drug delivery
soft tissue
rheumatoid arthritis
bone mineral density
cancer therapy
quantum dots
drug induced