C-Cbl reverses HER2-mediated tamoxifen resistance in human breast cancer cells.

Wei LiLing XuXiaofang CheHaizhou LiYe ZhangNa SongTi WenKezuo HouYi YangLu ZhouXing XinLu XuXue ZengSha ShiYunpeng LiuXiujuan QuTeng Yuee

Published in: BMC cancer (2018)

Our results suggested that c-Cbl can reverse tamoxifen resistance in HER2-overexpressing breast cancer cells by inhibiting the formation of the ER-c-Src-HER2 complex.

Keyphrases

breast cancer cells
endothelial cells
signaling pathway
tyrosine kinase
induced pluripotent stem cells
positive breast cancer