Genetic analysis and outcomes of Omani children with steroid-resistant nephrotic syndrome.
Mohamed S Al RiyamiIntisar Al AlawiBadria Al GaithiAnisa Al MaskariNaifain Al KalbaniNadia Al HashmiAisha Al BalushiMaryam Al ShahiSuliman Al SaidiMuna Al BimaniFahad Al HataliHolly MabillardJohn Andrew SayerPublished in: Molecular genetics & genomic medicine (2023)
NPHS2 and NPHS1 genetic variants were the most common inherited causes of SRNS in Omani children. However, patients with variants in several other SRNS causative genes were also identified. We recommend screening for all genes responsible for SRNS in all children who present with this phenotype, which will assist in clinical management decisions and genetic counseling for the affected families.