Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease.

Dana Shulman Serafima Dubnov Tamara Zorbaz Nimrod Madrer Iddo Paldor David A Bennett Sudha Seshadri Elliott J Mufson David S Greenberg Yonatan Loewenstein Hermona Soreq

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)

Our findings support CholinotRFs contributions to cholinergic regulation, predicting their involvement in AD sex-specific cholinergic loss and dementia.

Keyphrases

mild cognitive impairment
cognitive decline
cognitive impairment
cancer therapy