Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5).

Published in: Biomolecular NMR assignments (2019)

Retinal membrane guanylyl cyclase (RetGC) in photoreceptor rod and cone cells is regulated by a family of guanylyl cyclase activating proteins (GCAP1-7). GCAP5 is expressed in zebrafish photoreceptors and promotes Ca2+-dependent regulation of RetGC enzymatic activity that regulates visual phototransduction. We report NMR chemical shift assignments of the Ca2+-free activator form of GCAP5 (BMRB No. 27705).

Keyphrases

optical coherence tomography
signaling pathway
induced apoptosis
diabetic retinopathy
cell cycle arrest
optic nerve
magnetic resonance
high resolution
protein kinase
hydrogen peroxide
endoplasmic reticulum stress
pi k akt
cell death
immune response
binding protein
protein protein
solid state