Comparison of four commercial SARS-CoV-2 IgG immuno-assays in RT-PCR negative patients with suspect CT findings.
Jens Tomas Van PraetAnn-Sofie CoeneKris Van De MoortelePatrick DescheemaekerMarijke ReyndersPublished in: Infection (2020)
A subset of patients with Covid-19 presents with negative RT-PCR screening but suspect CT findings. Using four commercially available anti-SARS-CoV-2 IgG immuno-assays, we found this subset constituted 9.2% of all consecutively admitted outpatients with Covid-19 in our hospital. Clinical specificity for Covid-19 of some N protein-based immuno-assays was suboptimal, as positive results were observed in control patients with recent common human coronavirus, influenza B and adenovirus infections.
Keyphrases
- sars cov
- high throughput
- respiratory syndrome coronavirus
- image quality
- computed tomography
- dual energy
- contrast enhanced
- endothelial cells
- coronavirus disease
- healthcare
- positron emission tomography
- induced pluripotent stem cells
- emergency department
- magnetic resonance
- binding protein
- adverse drug
- amino acid
- electronic health record
- drug induced