Synthesis of Aromatic Sulfones from SO2 and Organosilanes Under Metal-free Conditions.

Niklas von WolffJoëlle CharXavier FrogneuxThibault Cantat

Published in: Angewandte Chemie (International ed. in English) (2017)

The conversion of SO2 into arylsulfones under metal-free conditions was achieved for the first time by reacting SO2 with (hetero)arylsilanes and alkylhalides in the presence of a fluoride source. The mechanism of this transformation was elucidated based on DFT calculations, which highlight the influence of SO2 in promoting C-Si bond cleavage.

Keyphrases

density functional theory
molecular dynamics
drinking water
amino acid
monte carlo