PD-L1-expressing macrophages play a protective role in the joint during arthritis.
Megan Kay WoodAbdel DaoudMonica Vladut TalorHannah Maryam KalinoskiDavid Matthew HughesCamille Marie JaimeJody Elizabeth HooperTaejoon WonDaniela ČihákováPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
macrophages with efferocytotic and anti-inflammatory characteristics protect the synovium from severe arthritis in the CIA mouse model. Tissue-protective PD-L1-expressing macrophages are also present in the human synovium at homeostasis and during rheumatoid arthritis. This article is protected by copyright. All rights reserved.