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B7-H3-Targeting Chimeric Antigen Receptors Epstein-Barr Virus-specific T Cells Provides a Tumor Agnostic Off-The-Shelf Therapy Against B7-H3-positive Solid Tumors.

Siok Ping YeoLindsay KuaJin Wei TanJoanna Kristyn LimFiona Hs WongMay Delos SantosChek-Meng PohAngeline Xh GohXin Yu KohXiaohua ZhouRavisankar RajarethinamQingfeng ChenZhisheng HerIvan D HorakLionel LowKar Wai Tan
Published in: Cancer research communications (2024)
Clinical application of EBVSTs armored with B7-H3-targeting CARs offer an attractive solution to translate off-the-shelf CAR T cells as therapy for solid tumors.
Keyphrases
  • epstein barr virus
  • diffuse large b cell lymphoma
  • cancer therapy
  • cell therapy
  • stem cells
  • bone marrow