Neonatal jaundice and autism spectrum disorder: a systematic review and meta-analysis.

Monica Lauridsen KujabiJesper P PetersenMette V PedersenErik T ParnerTine B Henriksen

Published in: Pediatric research (2021)

Meta-analysis of data from six low risk of bias studies indicated no association between neonatal jaundice and autism spectrum disorder. Previous studies show inconsistent results, which may be explained by unadjusted confounding and selection bias. Funnel plot suggested high risk of publication bias when including all studies. There is no evidence to suggest jaundice should be treated more aggressively to prevent autism.

Keyphrases

autism spectrum disorder
intellectual disability
case control
attention deficit hyperactivity disorder
electronic health record
machine learning
big data
newly diagnosed