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A Mosaic Variant in CTNNB1/β-catenin as a Novel Cause for Osteopathia Striata With Cranial Sclerosis.

Yentl HuybrechtsNatasha M Appelman-DijkstraEllen SteenackersWouter Van BeylenGeert R MortierGretl HendrickxWim Van Hul
Published in: The Journal of clinical endocrinology and metabolism (2024)
In conclusion, this study indicates that somatic variants in the CTNNB1 gene could explain the pathogenesis of unsolved cases of osteopathia striata.
Keyphrases
  • copy number
  • cell proliferation
  • genome wide
  • signaling pathway