Photoredox-Catalyzed Decarboxylative Oxidation of Arylacetic Acids.
Yota SakakibaraPhillippa CooperKei MurakamiKenichiro ItamiPublished in: Chemistry, an Asian journal (2018)
A photoredox-catalyzed decarboxylative oxidation of arylacetic acids, which are privileged scaffolds in pharmaceuticals, is reported herein. The established method is operationally simple and a variety of substrates are applicable, providing rapid access to dehomologated bioisosteres of common pharmaceuticals.