Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions.

Colm ElliottJerry S WolinskyStephen L HauserLudwig KapposFrederik BarkhofCorrado BernasconiWei WeiShibeshih BelachewDouglas L Arnold

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2018)

We suggest that SELs reflect chronic tissue loss in the absence of ongoing acute inflammation. SELs may represent a conventional brain MRI correlate of chronic active MS lesions and a candidate biomarker for smoldering inflammation in MS.

Keyphrases

multiple sclerosis
magnetic resonance imaging
oxidative stress
mass spectrometry
white matter
drug induced
contrast enhanced
respiratory failure
intensive care unit
diffusion weighted imaging
blood brain barrier
extracorporeal membrane oxygenation