Graft infusion of adipose-derived mesenchymal stromal cells to prevent rejection in experimental intestinal transplantation: A feasibility study.
Ane M AndresPablo StringaPaloma TalayeroMonica SantamariaMariano García-ArranzSoledad García Gómez-HerasCarlota Largo-AramburuRosa M Aras-LopezMaria Teresa Vallejo-CremadesLaura Guerra PastriánLuz VegaJose Luis EncinasManuel Lopez-SantamariaFrancisco Hernández-OliverosPublished in: Clinical transplantation (2021)
Ad-MSC did not prevent rejection when administered just before reperfusion. However, they showed immunomodulatory effects that could be relevant for a longer-term outcome. Interference between tacrolimus and the MSC effects should be addressed in further studies.