Autoantibodies in COVID-19 correlate with antiviral humoral responses and distinct immune signatures.
Patrick TaeschlerCarlo Cervia-HaslerYves ZurbuchenSara HaslerChristian PouZiyang TanSarah AdamoMiro E RaeberEsther BächliAlain RudigerMelina Stüssi-HelblingLars C HuberPetter BrodinJakob NilssonElsbeth Probst-MüllerOnur BoymanPublished in: Allergy (2022)
Highly sensitive indirect immunofluorescence assays revealed transient autoantibody production during acute SARS-CoV-2 infection, while the presence of autoantibodies in COVID-19 patients correlated with increased antiviral humoral immune responses and inflammatory immune signatures.
Keyphrases
- immune response
- sars cov
- systemic lupus erythematosus
- coronavirus disease
- respiratory syndrome coronavirus
- liver failure
- genome wide
- dendritic cells
- toll like receptor
- oxidative stress
- single cell
- cerebral ischemia
- aortic dissection
- living cells
- mass spectrometry
- intensive care unit
- fluorescent probe
- brain injury
- single molecule
- molecularly imprinted
- inflammatory response