N-Acetylcysteine Reduces ROS-Mediated Oxidative DNA Damage and PI3K/Akt Pathway Activation Induced by Helicobacter pylori Infection.

Chuan XieJian YiJing LuMuwen NieMeifang HuangJianfang RongZhenhua ZhuJiang ChenXiaoliang ZhouBimin LiHaiming ChenNong Hua Lu Xu Shu

Published in: Oxidative medicine and cellular longevity (2018)

An increased ROS level is a critical mechanism in H. pylori pathogenesis, and NAC may be beneficial for the treatment of H. pylori-related gastric diseases linked to oxidative DNA damage.

Keyphrases

dna damage
helicobacter pylori infection
dna repair
oxidative stress
helicobacter pylori
transcription factor
cell death
reactive oxygen species