Elevated Interleukin-6 Levels Are Associated With an Increased Risk of QTc Interval Prolongation in a Large Cohort of US Veterans.

Pietro Enea LazzeriniMichael CupelliAlessandra CartocciIacopo BertolozziViola SalviniRiccardo Accioli Fabio SalvadoriTommaso MarzottiDecoroso Verrengia Gabriele CeveniniStefania BisognoMaurizio BicchiGiovanni DonatiSciaila Bernardini Franco Laghi-Pasini Maurizio Acampa Pier Leopoldo CapecchiNabil El-SherifMohamed Boutjdir

Published in: Journal of the American Heart Association (2024)

Our data provide evidence that a high circulating IL-6 level is a robust risk factor for QTc prolongation in a large cohort of US veterans, supporting a potentially important arrhythmogenic role for this cytokine in the general population.

Keyphrases

drug induced
electronic health record
big data
machine learning
artificial intelligence