A single-dose strategy for immunization with live attenuated vaccines is an effective option before treatment initiation in multiple sclerosis patients.
Rene CarvajalCarmen TurXavier Martínez-GómezLuca BolloJuliana EsperalbaMarta RodriguezAgustín PappollaÁlvaro Cobo-CalvoPere CarbonellBlanca Borras-BemejoJordi RíoJoaquín CastillóNathane BragaNeus Mongay-OchoaJosé Ángel Rodrigo-PendásÁngela Vidal-JordanaGeorgina ArrambideBreogan Rodriguez AcevedoAnna ZabalzaLuciana MidagliaIngrid GalánManuel ComabellaJaume Sastre-GarrigaXavier MontalbanMar TintoreSusana Otero-RomeroPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2023)
An SDA of VAR and/or MMR vaccines could be sufficient to protect almost two-thirds of patients. Testing immunogenicity after a single dose of VZ and/or MMR could be included in routine clinical practice to achieve rapid immunization.