Clinical and cytopathological characteristics of HTLV-1+ hodgkin lymphoma.

Katsumi KobataShoichi KimuraYasuhito MihashiHiromi IwasakiShuichi NonakaShinji MatsumotoYasushi TakamatsuIlseung ChoiShigeto KawauchiKenji Ishitsuka Morishige Takeshita

Published in: Cancer medicine (2020)

HTLV-1+ HL showed typical small lymphoid cells with a low MIB1 labeling index in a background of Hodgkin and RS cells, with some scattered CD25+ and CCR4+ lymphocytes. In HTLV-1 endemic areas, distinguishing HTLV-1+ HL from HL-like ATLL is important because of their differing treatment strategies and prognoses.

Keyphrases

hodgkin lymphoma
induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
cell death
signaling pathway
peripheral blood