Computer-aided design of an eco-friendly imprinted polymer decorated sensors augmented by self-validated ensemble modeling designs for the quantitation of drotaverine hydrochloride in dosage form and human plasma.
Aziza E MostafaMaya S EissaAhmed ElsonbatyKhaled AttalaRanda A Abdel SalamGhada M HadadMohamed A AbdelshakourPublished in: Journal of AOAC International (2023)
This work presents the first ever application of both the innovative SVEM designs and MD/QM simulations in the optimization and fabrication of drotaverine-sensitive and selective MIP-decorated PVC sensors.
Keyphrases
- low cost
- reduced graphene oxide
- molecular dynamics
- quantum dots
- highly efficient
- ms ms
- solid phase extraction
- mass spectrometry
- liquid chromatography tandem mass spectrometry
- finite element analysis
- convolutional neural network
- tandem mass spectrometry
- high performance liquid chromatography
- monte carlo
- liquid chromatography
- deep learning
- virtual reality