Induction of a rat model of premature ovarian insufficiency using D-galactose feeding during the critical periods of development: A pilot study.

Marzieh Rostami DovomMahsa NoroozzadehNariman MosaffaAbbas PiryaeiAzita ZadevakiliMohammad Amin AbdollahifarFahimeh Ramezani Tehrani

Published in: International journal of reproductive biomedicine (2022)

As the birth weights of the offspring of our experimental and control groups were similar, it can be concluded that the reduction of ovarian follicles after prenatal exposure to D-galactose is due to the ovotoxicity of galactose. The results of our final study will provide more information about the rat POI model induced by prenatal exposure to D-galactose.

Keyphrases

pregnant women
oxidative stress
healthcare
metabolic syndrome
health information
gestational age
insulin resistance
pregnancy outcomes