Large differences in neonatal drug use between NICUs are common practice: time for consensus?

Robert B FlintFloor van BeekPeter AndriessenLuc J ZimmermannKian D LiemIrwin K M ReissRonald de GrootDick TibboelDavid Marinus BurgerSinno H P Simonsnull null

Published in: British journal of clinical pharmacology (2018)

We showed that drug use varies widely in neonatal clinical practice. The drug classes with the highest proportion of off-label drugs in relation to neonatal age showed the largest differences between NICUs, i.e. cardiovascular and nervous system drugs. Drug research in neonates should receive high priority to guarantee safe and appropriate medicines and optimal treatment.

Keyphrases

clinical practice
primary care
healthcare
drug induced
emergency department
quality improvement