Cognitive impairment in obese rat model: role of glial cells.
Reham M WahidWalaa M SamySherein F El-SayedPublished in: International journal of obesity (2005) (2021)
Many factors contribute to obesity associated cognitive impairment. In our study, we figured out the crucial roles of glial cells including microglial activation and oligodendrocytes affection with other underlying mechanisms including oxidative stress and hippocampal inflammation.
Keyphrases
- cognitive impairment
- induced apoptosis
- oxidative stress
- cell cycle arrest
- metabolic syndrome
- weight loss
- neuropathic pain
- type diabetes
- insulin resistance
- adipose tissue
- inflammatory response
- dna damage
- signaling pathway
- bariatric surgery
- ischemia reperfusion injury
- body mass index
- weight gain
- diabetic rats
- lipopolysaccharide induced
- subarachnoid hemorrhage
- cerebral ischemia
- obese patients
- heat stress