The role of vascular smooth muscle cells in the development of aortic aneurysms and dissections.

Karlijn B RomboutsTara A R van MerrienboerJohannes C F KetNatalija BogunovicJolanda van der VeldenKak Khee Yeung

Published in: European journal of clinical investigation (2021)

This review underscores a central role of vSMC dysfunction in abdominal and thoracic AA and AD development and progression. Further research focused on vSMC dysfunction in the aortic wall is necessary to find potential targets for noninvasive AA and AD treatment options.

Keyphrases

vascular smooth muscle cells
aortic valve
angiotensin ii
left ventricular
pulmonary artery
spinal cord
aortic dissection
heart failure
spinal cord injury
risk assessment
atrial fibrillation