[A comparative study of the P300 wave and evoked theta-rhythm in schizophrenia and personality disorders].

The decrease in P300 amplitude, prolongation of P300 latency, and reduction in the evoked theta-band power and coherence were revealed in all groups of patients compared to healthy subjects. These changes were spatially generalized and the most pronounced in schizophrenic patients. In patients with personality and schizotypal disorders, the changes had a local character, and didn't differ significantly when the groups were compared. The results show the gradual cognitive decline as follows: healthy patients, patients with schizotypal disorder, patients with personality disorder, and patients with schizophrenia. Such cognitive decline might be in line with the reduction of critical and prognostic abilities.