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Association between comorbidities and extraglandular manifestations in primary Sjögren's syndrome: a multicenter cross-sectional study.

Yuying ZhangMengtao LiLiyun ZhangQin LiPinting YangXiaodan KongXinwang DuanMiaojia ZhangXiaomei LiYongfu WangJian XuYanhong WangEvelyn HsiehJiuliang ZhaoDong XuYan ZhaoXiaofeng Zeng
Published in: Clinical rheumatology (2020)
The presence of extraglandular manifestations in pSS was associated with an increased comorbidity burden, especially cardiovascular disease, thyroid disorder, and fragility fracture. Key Points • This is the first study assessing the association between extraglandular manifestations and comorbidity burden based on the largest pSS registry in China. • Patients with multiple extraglandular manifestations tend to have increased comorbid cardiovascular disease, thyroid disorder, and fragility fracture.
Keyphrases
  • cardiovascular disease
  • type diabetes
  • cardiovascular risk factors
  • risk factors
  • case report
  • cardiovascular events
  • rheumatoid arthritis
  • systemic lupus erythematosus
  • double blind