From Waste to Health: Olive Mill Wastewater for Cardiovascular Disease Prevention.
Laura Beatrice MattioliIvan CorazzaRoberta BudriesiSilvana HreliaMarco MalagutiCristiana CalicetiRosa AmorosoCristina MaccalliniPasquale CrupiMaria Lisa ClodoveoMarilena MuragliaAlessia CarocciRoberta TardugnoAlexia BarbarossaFilomena Faustina Rina CorboPublished in: Nutrients (2024)
Waste from the agri-food chain represents a valuable reservoir of organic compounds with health-promoting properties. Momast Plus 30 Bio (MP30B) is a derivative obtained from olive-oil wastewater. Its enrichment in hydroxytyrosol (HT) via a patented technique has paved the way for its potential application as a dietary supplement in preventing cardiovascular diseases. MP30B demonstrates no significant alteration in cardiac and vascular parameters in "ex vivo" studies. However, it exhibits a strong ability to remove reactive oxygen species and exerts anti-inflammatory effects, notably reducing the concentration of iNOS and mitigating heart infections in "in vitro" experiments. Furthermore, MP30B slightly decreases the stiffness of the "ex vivo" thoracic aorta, potentially resulting in lowered arterial pressure and enhanced energy transfer to a normal ventricle. Based on these findings, we posit MP30B as a promising extract for cardiovascular disease prevention, and its specific antibacterial properties suggest its utility in preventing cardiac infections.
Keyphrases
- cardiovascular disease
- energy transfer
- healthcare
- reactive oxygen species
- public health
- mental health
- heavy metals
- left ventricular
- wastewater treatment
- pulmonary artery
- type diabetes
- health information
- cardiovascular events
- cardiovascular risk factors
- human health
- health promotion
- heart failure
- sewage sludge
- quantum dots
- aortic valve
- anti inflammatory
- municipal solid waste
- anaerobic digestion
- mitral valve
- water soluble
- oxidative stress
- spinal cord
- pulmonary hypertension
- coronary artery disease
- atrial fibrillation
- case control
- spinal cord injury
- silver nanoparticles
- climate change