The Epstein-Barr virus EBNA1 protein modulates the alternative splicing of cellular genes.

Simon BoudreaultVictoria E S ArmeroMichelle S ScottJean-Pierre PerreaultMartin Bisaillon

Published in: Virology journal (2019)

The EBNA1 protein can modulate the AS profiles of numerous cellular genes. Interestingly, this modulation protein does not require the RNA binding activity of EBNA1. Overall, these findings underline the novel role of EBNA1 as a cellular splicing modulator.

Keyphrases

epstein barr virus
diffuse large b cell lymphoma
protein protein
binding protein
genome wide
amino acid
gene expression
small molecule
dna methylation
genome wide identification