Spatial Metabolomics Identifies Distinct Tumor-Specific Subtypes in Gastric Cancer Patients.

Jun WangThomas KunzkeVerena M PradeJian ShenAchim BuckAnnette FeuchtingerIvonne HaffnerBirgit LuberDrolaiz H W LiuRupert LangerFlorian LordickNa SunAxel K Walch

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Patient subtypes derived by tissue-based spatial metabolomics are a valuable addition to existing gastric cancer molecular classification systems. Metabolic differences between the subtypes and their associations with molecular features could provide a valuable tool to aid in selecting specific treatment approaches.

Keyphrases

end stage renal disease
mass spectrometry
ejection fraction
newly diagnosed
chronic kidney disease
machine learning
peritoneal dialysis
genome wide
case report
single molecule
gene expression
combination therapy
smoking cessation