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Neuropeptide Y1 receptor antagonist but not neuropeptide Y itself increased bone mineral density when locally injected with hyaluronic acid in male Wistar rats

Muhammer Özgür ÇevikPetek KorkusuzNecdet Sağlam
Published in: Turkish journal of medical sciences (2020)
Local administration of NPY and NPY1 antagonists may hold regulating potential of BMD and bone formation. NPY1 antagonist caused new bone formation in trabecular bone when applied locally. NPY dissolved in HA however can be used to suppress bone formation.
Keyphrases
  • bone mineral density
  • hyaluronic acid
  • postmenopausal women
  • body composition
  • organic matter