Fetal inflammation induces acute immune tolerance in the neonatal rat hippocampus.
Garima SinghBradley J SeguraMichael K GeorgieffTate GisslenPublished in: Journal of neuroinflammation (2021)
Prenatal LPS exposure induced immune tolerance to subsequent postnatal LPS exposure in the hippocampus. Microglia demonstrate a robust inflammatory response to postnatal LPS, but only a partial immune tolerance response.
Keyphrases
- inflammatory response
- lipopolysaccharide induced
- lps induced
- toll like receptor
- oxidative stress
- preterm infants
- anti inflammatory
- liver failure
- drug induced
- diabetic rats
- cognitive impairment
- cerebral ischemia
- hepatitis b virus
- immune response
- spinal cord injury
- respiratory failure
- blood brain barrier
- subarachnoid hemorrhage
- acute respiratory distress syndrome
- aortic dissection
- neuropathic pain
- spinal cord
- extracorporeal membrane oxygenation