An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome.
Maria L TaylorKacie J HoytJoseph HanLeslie BensonSiobhan CaseMia T ChandlerMargaret H ChangCraig PlattEzra M CohenMegan Day-LewisFatma DedeogluMark GormanJonathan S HausmannErin JanssenPui Y LeeJeffrey LoGregory P PriebeMindy S LoEsra MeidanPeter A NigrovicJordan E RobertsMary Beth F SonRobert P SundelMaria AlfieriJenny Chan YeunDamilola M ShobiyeBarbara DegarJoyce C ChangOlha HalyabarMelissa M HazenLauren A HendersonPublished in: The Journal of rheumatology (2022)
While the observed improvements may be partially attributed to advances in treatment of MAS-HLH that have accumulated over time, this analysis also suggests that a multidisciplinary treatment pathway for MAS-HLH contributed meaningfully to favorable patient outcomes.