Association of positive airway pressure termination with mortality and non-fatal cardiovascular events in patients with obstructive sleep apnoea.

AbdelKebir SabilClaire LaunoisWojchiech TrzepizurFrançois GoupilThierry PigeanneSandrine LaunoisLaurène Leclair-VisonneauPhilippe MassonAcya Bizieux-ThaminySandrine KerbatJean-François TimsitFrédéric Gagnadouxnull null

Published in: Thorax (2024)

In this multicentre clinical-based cohort involving 4188 patients with OSA, PAP termination compared with adherent PAP continuation was associated with an increased risk of MACE. More research is needed to determine whether support programmes on PAP adherence could improve CV outcomes.

Keyphrases

positive airway pressure
cardiovascular events
obstructive sleep apnea
sleep apnea
coronary artery disease
cardiovascular disease
clinical trial
study protocol
type diabetes
sleep quality
glycemic control
metabolic syndrome
depressive symptoms
skeletal muscle
risk factors
double blind
insulin resistance