A closed-loop multi-level model of glucose homeostasis.
Cansu UlusekerGiulia SimoniLuca MarchettiMarco DaurizAlice MatoneCorrado PriamiPublished in: PloS one (2018)
The combination of a multi-level and closed-loop modeling approach provided a fair dynamic description of the core determinants of glucose homeostasis at both cellular and systemic scales. This model architecture is intrinsically open to incorporate supplementary layers of specifications describing further individual components influencing glucose metabolism.