Determination of oxidative stress level and some antioxidant activities in refractory epilepsy patients.
Abdullah YilgorCanan DemirPublished in: Scientific reports (2024)
The aim of this study was to determine the levels of superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) in patients with refractory epilepsy. Serum superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) levels were determined using the spectrophotometer method. Refractory epilepsy patients' serum superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) levels were statistically significant compared to the healthy control group (p < 0.05). In conclusion, superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH) and malondialdehyde (MDA) levels may play an important role in the etiopathogenesis of refractory epilepsy. This study was the first to investigate some parameters in refractory epilepsy disease.
Keyphrases
- end stage renal disease
- oxidative stress
- chronic kidney disease
- ejection fraction
- newly diagnosed
- breast cancer cells
- hydrogen peroxide
- peritoneal dialysis
- fluorescent probe
- amyotrophic lateral sclerosis
- prognostic factors
- patient reported outcomes
- cell proliferation
- induced apoptosis
- temporal lobe epilepsy
- diabetic rats