Split scar sign to predict complete response in rectal cancer after neoadjuvant chemoradiotherapy: systematic review and meta-analysis.
Giovanni Brondani TorriCamila Piovesan WiethanFelipe Welter LangerGuilherme Strieder de OliveiraAlice Villa Bella MeirellesNatally HorvatJustin Ruey TseAdriano Dias BassoStephan Philip Leonhardt AltmayerPublished in: European radiology (2023)
•Fifteen to 50% of rectal cancer patients achieve complete response after neoadjuvant chemoradiation and may be eligible for a watch-and-wait strategy. •The split scar sign has high specificity for a complete response. •This imaging finding is valuable to select candidates for organ-sparing management.