Design and characterization of a SYBR Green I-based melting curve method for investigation of HER2I655V polymorphism in breast cancer.

D Desrianinull AzamrisShabrina S GhaissaniSenja R KinantiMuhammad A WarismanN Fitria

Published in: Journal, genetic engineering & biotechnology (2021)

This approach may be considered as simple, rapid, and low cost supporting the rapid study of HER2 epidemiology. Furthermore, the developed methods potentially facilitate clinicians in dealing with breast cancer patients, especially in considering about the cardiotoxicity effect of trastuzumab.

Keyphrases

low cost
high resolution
loop mediated isothermal amplification
epidermal growth factor receptor
risk factors
mass spectrometry