ED-71 Improves Bone Mass in Ovariectomized Rats by Inhibiting Osteoclastogenesis Through EphrinB2-EphB4-RANKL/OPG Axis.

Ke Wang Yuying KouXing RongLingling WeiJingyuan LiHongrui LiuMinqi Li Hui Song

Published in: Drug design, development and therapy (2024)

ED-71 inhibits osteoclastogenesis through EphrinB2-EphB4-RANKL/OPG axis, improving bone mass in ovariectomized rats. PI3K/AKT pathway is involved this process.

Keyphrases

bone loss
emergency department
signaling pathway
bone mineral density
inflammatory response
postmenopausal women
lps induced