The presence of IFL3/4 rs12979860 C allele influences the in vitro IP-10 production by mononuclear cells from patients with systemic lupus erythematosus.
Y Juárez-VicuñaJ Pérez-RamosL Adalid-PeraltaF SánchezR SpringallJ Villaseñor-JassoM S Sixtos-AlonsoM A Ballinas-VerdugoR Márquez-VelascoR BojalilLuis M Amezcua GuerraFausto Sánchez-MuñozPublished in: Lupus (2020)
Although IFNL3/4 rs12979860 allele C does not appear to influence serum IP-10 levels in SLE, it plays an important role in the production of IP-10 by peripheral blood mononuclear cells after IFNα stimulation.