Chemoresistant ovarian cancer enhances its migration abilities by increasing store-operated Ca2+ entry-mediated turnover of focal adhesions.

Ho-Kai HuangYi-Hsin LinHeng-Ai ChangYi-Shyun LaiYing-Chi ChenSoon-Cen HuangCheng-Yang ChouWen-Tai Chiu

Published in: Journal of biomedical science (2020)

Our findings describe the role of SOCE in chemoresistance-mediated focal adhesion turnover, cell migration, and viability. Consequently, SOCE might be a promising therapeutic target in epithelial ovarian cancer.

Keyphrases

cell migration
bone mineral density
biofilm formation
staphylococcus aureus
protein kinase