A novel role of Krüppel-like factor 8 as an apoptosis repressor in hepatocellular carcinoma.

Ming-Da WangHao XingChao LiLei LiangHan WuXin-Fei XuLi-Yang SunMeng-Chao WuFeng ShenTian Yang

Published in: Cancer cell international (2020)

Our work suggests a novel role and mechanism for KLF8 in the regulation of cell apoptosis in HCC and facilitates the discovery of potential therapeutic targets for HCC treatment.

Keyphrases

oxidative stress
small molecule
cell proliferation
endoplasmic reticulum stress
cell death
transcription factor
combination therapy