Specific immune biomarker monitoring in two children with severe IgA nephropathy and successful therapy with immunoadsorption in a rapidly progressive case.

Alexandra CambierClaire DossierJulien HoganVéronique BaudouinAnne MaisinAnne CoudercTheresa KwonPatrick J GleesonRenato C Monteiro

Published in: Pediatric nephrology (Berlin, Germany) (2022)

In conclusion, sequential biomonitoring of Gd-IgA1, IgA-immune complexes, and sCD89 in cIgAN was found to be valuable, by correlating with clinical features and glomerular proliferative lesions in cIgAN. These biomarkers could represent useful tools to evaluate kidney injury without repeat kidney biopsies.

Keyphrases

multiple sclerosis
young adults
early onset
stem cells
mesenchymal stem cells
ultrasound guided
high glucose
cell therapy
bone marrow
drug induced
chemotherapy induced