Liver Bacterial Colonization in Patients with Obesity and Gut Dysbiosis.
Lucia PaianoManuela MastronardiGiuseppina CampiscianoNatalia RossoBiagio CasagrandaManola ComarNicolò de ManziniSilvia PalmisanoPublished in: Obesity surgery (2023)
To the best of our knowledge, this is the first study reporting the presence of bacterial genome in a liver biopsy on bariatric patients, instead of the microbe-associated molecular patterns. Notably, in literature, the presence of Roseburia intestinalis in stool samples has been shown to prevent intestinal inflammation playing its role in the gut barrier integrity. In our population, the Roseburia reduction was associated with the presence of bacterial genome in the liver, probably related to a greater permeability of the gut and vascular barriers.
Keyphrases
- weight loss
- end stage renal disease
- newly diagnosed
- ejection fraction
- type diabetes
- systematic review
- healthcare
- metabolic syndrome
- insulin resistance
- prognostic factors
- genome wide
- endothelial cells
- roux en y gastric bypass
- emergency department
- gene expression
- ultrasound guided
- weight gain
- body mass index
- adipose tissue
- patient reported
- adverse drug