Attenuation of Doxorubicin-Induced Small Intestinal Mucositis by Pectins is Dependent on Pectin's Methyl-Ester Number and Distribution.

Martin BeukemaÉva JermendiTaco KosterKohji KitaguchiBart J de HaanMarco Alexander van den BergMarijke M FaasHenk Arie ScholsPaul de Vos

Published in: Molecular nutrition & food research (2021)

These pectin structures with stronger TLR2-inhibiting properties may prevent the development of doxorubicin-induced intestinal damage in patients undergoing chemotherapeutic treatment with doxorubicin.

Keyphrases

patients undergoing
drug delivery
high glucose
diabetic rats
cancer therapy
oxidative stress
toll like receptor
signaling pathway
inflammatory response
high resolution
endothelial cells
radiation induced
cell wall
combination therapy
smoking cessation