Brain perfusion in dementia with Lewy bodies and Alzheimer's disease: an arterial spin labeling MRI study on prodromal and mild dementia stages.
Daniel RoquetMarion SourtyAnne BotzungJean-Paul ArmspachFrédéric BlancPublished in: Alzheimer's research & therapy (2016)
Our results are consistent with previous studies. We extend the scope of those studies by integrating prodromal DLB patients and by describing both hypo- and hyperperfusion in DLB. While decreases in perfusion may relate to functional impairments, increases might suggest a functional compensation of some brain areas.
Keyphrases
- contrast enhanced
- parkinson disease
- mild cognitive impairment
- end stage renal disease
- white matter
- cognitive impairment
- ejection fraction
- resting state
- newly diagnosed
- magnetic resonance imaging
- chronic kidney disease
- cognitive decline
- prognostic factors
- case control
- magnetic resonance
- patient reported outcomes
- room temperature
- multiple sclerosis
- diffusion weighted imaging