Effect of Multiple Doses of Intravenous Tranexamic Acid on Perioperative Blood Loss in Total Knee Arthroplasty: A Randomized Controlled Study.

Bing-Xin KangYu-Lin LiHui XuChen-Xin GaoSheng ZhongJing ZhangJun XieSong-Tao SunXi-Rui XuChi ZhaoYing-Hui MaWei-Tao ZhaiLian-Bo XiaoXiao-Xue Hu

Published in: Orthopaedic surgery (2020)

Three doses of postoperative IV-TXA decreased blood loss and diminished the postoperative inflammatory and fibrinolytic response more than a single dose or two doses in elderly patients following TKA without increasing the incidence of adverse events.

Keyphrases

total knee arthroplasty
patients undergoing
total hip
risk factors
high dose
cardiac surgery
low dose