Chemotherapy improves distant control in localized high-grade soft tissue sarcoma of the extremity/trunk.

Victoria T RizkArash O NaghaviAndrew S BrohlDavid M JoyceOdion BinitieYoungchul KimJohn P HannaJennifer SwankRicardo J GonzalezDamon R ReedMihaela Druta

Published in: Clinical sarcoma research (2020)

In patients with localized STS > 5 cm, the high-grade subset had a distant control benefit with the addition of chemotherapy, leading to improved progression free survival. This is more pronounced with the use of MAI and should be considered in patients eligible for this regimen.

Keyphrases

high grade
free survival
low grade
end stage renal disease
ejection fraction
lymph node
locally advanced
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
squamous cell carcinoma
radiation therapy
patient reported outcomes
patient reported