TMEM88 modulates the secretion of inflammatory factors by regulating YAP signaling pathway in alcoholic liver disease.

Liang-Yun LiChen-Chen YangSu-Wen LiYu-Min LiuHao-Dong LiShuang HuHong ZhouJin-Liang WangHang ShenXiao-Ming MengJun LiTao Xu

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2020)

All in all, these experimental outcomes indicated that TMEM88 had an indispensable impact on EtOH-induced secretion of inflammatory cytokines (IL-6 and IL-1β) in RAW264.7 cells through YAP signaling pathway.

Keyphrases

signaling pathway
induced apoptosis
pi k akt
cell cycle arrest
oxidative stress
endoplasmic reticulum stress
epithelial mesenchymal transition
diabetic rats
liver injury
high glucose
drug induced
type diabetes
cell proliferation
adipose tissue
skeletal muscle