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Relative leucocyte telomere length is associated with incident end-stage kidney disease and rapid decline of kidney function in type 2 diabetes: analysis from the Hong Kong Diabetes Register.

Feifei ChengAndrea On Yan LukHongjiang WuClaudia Ha-Ting TamCadmon K P LimBaoqi FanGuozhi JiangLuke CarrollAimin YangEric S H LauAlex C W NgHeung-Man LeeElaine Y K ChowAlice Pik-Shan KongAnthony C KeechMugdha V JoglekarWing-Yee SoAnandwardhan A HardikarJuliana Chung Ngor ChanAndrzej S JanuszewskiRonald C W Ma
Published in: Diabetologia (2021)
rLTL is independently associated with incident ESKD and rapid eGFR loss in individuals with type 2 diabetes. Telomere length may be a useful biomarker for the progression of kidney function and ESKD in type 2 diabetes.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • small cell lung cancer
  • loop mediated isothermal amplification
  • insulin resistance
  • epidermal growth factor receptor
  • tyrosine kinase
  • skeletal muscle