A Retrospective Analysis of the De Ritis Ratio in Muscle Invasive Bladder Cancer, with Focus on Tumor Response and Long-Term Survival in Patients Receiving Neoadjuvant Chemotherapy and in Chemo Naïve Cystectomy Patients-A Study of a Clinical Multicentre Database.
Victoria ErikssonOscar HolmkvistYlva HugeMarkus JohanssonFarhood AlamdariJohan SvenssonFiras AljaberyAmir SherifPublished in: Journal of personalized medicine (2022)
A high pre-treatment De Ritis ratio is on a population level, associated with increased mortality post-RC in endpoints DFS, CSS and OS. Associations decrease over time and require further investigations to determine how strong the associations are as meaningful prognostic markers for long-term mortality in MIBC. The ratio is not suitable for downstaging-prediction.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- muscle invasive bladder cancer
- cardiovascular events
- end stage renal disease
- lymph node
- sentinel lymph node
- newly diagnosed
- ejection fraction
- risk factors
- prognostic factors
- rectal cancer
- squamous cell carcinoma
- photodynamic therapy
- coronary artery disease
- radiation therapy
- robot assisted
- type diabetes
- patient reported outcomes
- emergency department
- adverse drug
- electronic health record